ALERT

 

Due to the evolving Coronavirus response, the hours of operation at Perelman School of Medicine cores and shared resources may be limited.  Please contact the Penn core facility directly for more information. 

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Molecular Profiling Facility

Notice: Penn Genomic Analysis Core will be opening for all services on June 1st, 2020 in accordance with the guidance from Perelman School of Medicine’s Phase I reopening plan. During this time we will be accepting samples for DNA and  RNA molecular profiling at different scales (microarray, Fluidigm, real-time PCR) DNA, RNA extraction,  Sanger, molecular biology work, NGS, BioAnalyzer, fragment analysis etc.

Please contact Hetty Rodriquez hettymr@pennmedicine.upenn.edu
for DNA and  RNA molecular profiling at different scales (microarray, Fluidigm, real-time PCR), DNA and RNA extraction etc.

All  inquiries or questions about our services please contact:

Tapan Ganguly (Facility Director) gangulyt@pennmedicine.upenn.edu

Hetty Rodriquez hettymr@pennmedicine.upenn.edu

 

Overview of Services

The Molecular Profiling Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. The Facility offers a range of cost and performance options suitable for a variety of experimental projects. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment.

The core supports quantitative RNA profiling on Affymetrix GeneChips and the high-throughput Gene Titan instrument, Luminex FlexMap 3D, Fluidigm BioMark HD, and the ABI QS 12K real-time PCR machine.
 
DNA profiling is offered on Affymetrix SNP GeneChips and the high-throughput Gene Titan instrument, Fluidigm BioMark HD, and the ABI QS 12K.
 
The Agilent aCGH platform provides genome-wide chromosomal analysis.
 
Comprehensive bioinformatics services are available for datasets from the core or from any source. Analyses are customized based on experimental design and prioritized goals. Specification and delivery of results are provided via face-to-face meetings.
 
Core users benefit from consultation and training available throughout their projects, including during experimental design and budget development, grant preparation, sample accrual, data management and analyses, and manuscript preparation.

Guide to ordering services

Details of how to use iLab to order services are available in this User Guide. External users should use this guide.

Leadership

Tapan Ganguly, PhD, Director, B16 Anat-Chem basement, gangulyt@pennmedicine.upenn.edu, (215) 573-7238 

Location and hours of operation

Hours Location

Monday- Friday     
9:00am-5:00pm 

57 and 68 John Morgan Building
University of Pennsylvania
3620 Hamilton Walk
Philadelphia, PA 19104

Links and Resources

  1. Technology
  2. Bioinformatics
  3. References
  4. Frequently Asked Questions

Contacts

Name Role Phone Email Location
Tapan Ganguly, PhD
Director
 
(215) 573-7238
 
gangulyt@pennmedicine.upenn.edu
 
B16 Anat-Chem basement
 
John Tobias, PhD
Technical Director - Bioinformatics
 
(215) 573-4791
 
jtobias@pennmedicine.upenn.edu
 
9-154 Smilow Center
 
Hetty Rodriguez, MS
Lab Manager
 
(215) 573-6316
 
hettymr@pennmedicine.upenn.edu
 
68 John Morgan basement