Penn Genomics and Sequencing Core - Molecular Profiling Laboratory

We accept samples for DNA and RNA molecular profiling at different scales (microarray, Fluidigm, real-time PCR) DNA, RNA extraction, NGS Library Preparation, Sanger sequencing, molecular biology work, NGS, BioAnalyzer, fragment analysis etc.

Please contact Tapan Ganguly (Facility Director) gangulyt@pennmedicine.upenn.edu with inquiries.

Overview of Services

The Molecular Profiling Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. The Facility offers a range of cost and performance options suitable for a variety of experimental projects. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment.

The core supports quantitative RNA profiling on Affymetrix GeneChips and the high-throughput Gene Titan instrument, Luminex FlexMap 3D, Fluidigm BioMark HD, and the ABI QS 12K real-time PCR machine.

DNA profiling is offered on Affymetrix SNP GeneChips and the high-throughput Gene Titan instrument, Fluidigm BioMark HD, and the ABI QS 12K.

The Agilent aCGH platform provides genome-wide chromosomal analysis.

Comprehensive bioinformatics services are available for datasets from the core or from any source. Analyses are customized based on experimental design and prioritized goals. Specification and delivery of results are provided via face-to-face meetings.

Core users benefit from consultation and training available throughout their projects, including during experimental design and budget development, grant preparation, sample accrual, data management and analyses, and manuscript preparation.

Guide to ordering services

Details of how to use iLab to order services are available in this User Guide. External users should use this guide.

Research Resource Identifier (RRID)

Our RRID is: RRID:SCR_024999. Please cite us using this identifier when publishing your results.

Leadership

Tapan Ganguly, PhD, Director, B16 Anat-Chem basement, gangulyt@pennmedicine.upenn.edu, (215) 573-7238

Location and hours of operation

Hours	Location
Monday- Friday 9:00am-5:00pm	57 and 68 John Morgan Building University of Pennsylvania 3620 Hamilton Walk Philadelphia, PA 19104

Links and Resources

Contacts

Name	Role	Phone	Email	Location
Tapan Ganguly, PhD	Director	(215) 573-7238	gangulyt@pennmedicine.upenn.edu	B16 Anat-Chem basement
John Tobias, PhD	Technical Director - Bioinformatics	(215) 573-4791	jtobias@pennmedicine.upenn.edu