Due to the evolving Coronavirus response, the hours of operation at Perelman School of Medicine cores and shared resources may be limited.  Please contact the Penn core facility directly for more information. 

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Next-Generation Sequencing Core

COVID-19 Operating Level

Following the guidelines of the UPenn PSOM we are operating with limitations.

We are open for Phase I operations as of June 8, 2020.

See here for a description of the limitations and services offered in our current operating mode.


Overview of Services

We offer comprehensive high-throughput sequencing services from experiment design to basic data analysis.

This includes RNA extraction, library preparation, sample quality checks, and Illumina sequencing on our NovaSeq, NextSeq, or MiSeq.

All three of these sequencers can be operated by clients in a self-service mode or by NGSC staff.

You can request training on the machines on the Request Services tab above.

We perform both bulk and single-cell experiments using our 10x Chromium controller.

We can generate very long read data with our Oxford Nanopore Technologies minION sequencer.

Existing NGSC Clients

We are using iLab for equipment schedulingstarting an experiment, and for billing.

The science, quality checks, data delivery, etc. remains at our NGSC Website.

You will still need to use your NGSC accounts.

New NGSC Clients

Start by reviewing our FAQ and how we work.

New customers are encouraged to schedule a consultation through this calendar.

The PI and investigator will need accounts.

Additional information can be reviewed at the full core website.

Sample Drop-off Hours and Location

Drop-off Hours                                          Location                                                                                        
Tuesday - Friday 11 AM -12 PM     

Monday - Thursday 3 AM - 4 PM 
12-160 Smilow

3400 Civic Center Blvd., Philadelphia, PA 19104


Make your remittance payable to Trustees of the University of Pennsylvania, Attn: Jeffrey Griffin.

Other details pending.

Links and Resources

  1. Core Website
  2. Consultation Calendar
  3. Email us


Name Role Phone Email Location
Jonathan Schug, Ph.D.
Technical Director
215 898 0773
12-156 Smilow
Klaus Kaestner, Ph.D.