Welcome!
ALERT For system help please email Penn’s iLab support at: iLab.Support@pennmedicine.upenn.edu
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The Penn Genomics and Sequencing Core (PGSC) provides a spectrum of sequencing, genomics and molecular biological services with a team of highly experienced and trained professionals under a Director and Technical Director. The services include consultation on experimental design to performing experiment to downstream data analyses.
We offer Next-Generation Sequencing on multiple platforms:
Short Read - Illumina NovaSeq X Plus, NextSeq 2000 and MiSeq
Long Read - PacBio Revio and Oxford Nanopore MinION
This includes DNA/RNA extraction from different sources, library preparation with quality control, and sequencing followed by bioinformatics.
Applications include mRNA-Seq, total RNA-Seq, small RNA-Seq, WGS, targeted sequencing, ChIP-Seq on X Plus; WGS and whole methylome on PacBio etc.
For single-cell genomics we use 10X Genomics Controller; the applications include scRNA-Seq and snRNA-Seq. Soon we are going to introduce multiplexed scRNA-Seq. Multiome including scATAC-Seq are under development.
Bioinformatics support is available for both core and externally generated datasets.
Targeted molecular profiling including genotyping and gene expression is performed using ThermoFisher QS6 Pro. Mouse genotyping is done using PCR-based approach.
For further information please contact Director, Tapan Ganguly, gangulyt@pennmedicine.upenn.edu and Technical Director, Erik Toorens, toorens@pennmedicine.upenn.edu.
Charges for Major NGS Services
| Illumina NovaSeqX+ Pricing as of 7/1/2026 | Price |
| 1.5B 100 cycle | $ 2,903.04 |
| 1.5B 200 cycle | $ 3,540.35 |
| 1.5B 300 cycle | $ 3,795.28 |
| 1.5B 600 cycle | $ 6,687.50 |
| 5B 100 cycle | $ 3,853.26 |
| 5B 200 cycle | $ 4,725.12 |
| 5B 300 cycle | $ 5,341.50 |
| 10B 100 cycle | $ 7,565.25 |
| 10B 200 cycle | $ 9,050.25 |
| 10B 300 cycle | $ 10,150.25 |
| 25B 100 cycle | $ 16,843.75 |
| 25B 200 cycle | $ 20,693.75 |
| 25B 300 cycle | $ 23,416.25 |
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| Illumina Ready to Run NovaSeqX+ Pricing as of 7/1/2026 | Price |
| 1.5B 100 cycle | $ 1,178.65 |
| 1.5B 200 cycle | $ 1,306.25 |
| 1.5B 300 cycle | $ 1,471.25 |
| 1.5B 600 cycle | $ 1,750.00 |
| 5B 100 cycle | $ 1,196.25 |
| 5B 200 cycle | $ 1,416.25 |
| 5B 300 cycle | $ 1,581.25 |
| 10B 100 cycle | $ 1,196.25 |
| 10B 200 cycle | $ 1,416.25 |
| 10B 300 cycle | $ 1,581.25 |
| 25B 100 cycle | $ 1,581.25 |
| 25B 200 cycle | $ 2,296.25 |
| 25B 300 cycle | $ 2,846.25 |
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| PacBio Services | Price |
| SMRT Cell Sequencing | $2161.06 |
| SMRT Bell 3.0 Library (first) | $862.46 |
| SMRT Bell 3.0 Library (additional) | $449.96 |
| IsoSeq/Kinnex Library (first) | $1430.00 |
| IsoSeq/Kinnex Library (additional) | $385.00 |
Bioinformatics
Comprehensive analytical services are provided by John Tobias (Technical Director - Bionformatics) for datasets from the core or from any source. Experimental design consultation is without charge. Customized analysis pipelines are built (hourly fee-for-service) based on experimental design and prioritized goals. Please use this link to schedule a meeting.
Other Penn Resources:
DOM DRC Functional Genomics Core - Jonathan Schug and Kirill Batmanov - Members of the Institute for Diabetes and Metabolism's (IDOM) Diabetes Research Center (DRC) can get a wide range of bioinformatics services via the Functional Genomics Core (FGC).
IBI - Bioinformatics Core - Taehyong Kim - The Bioinformatics Core in the Institute for Biomedical Informatics offers a wide range of services. See the BiC website for more information.
Try these new links for help before, during, and after working with the NGSC.
PSOM iLab help - links to help for BAs and PIs
FAQs - answers to common questions.
URLs - links into the websites of Illumina, 10X Genomics, and others
Accounts for iLab and the NGSC data website are distinct and must be set up separately for PI and investigator.
Letters of Support
Contact us for letters of support for grant applications.
POs
Make your remittance payable to Trustees of the University of Pennsylvania, Attn: Jeffrey Griffin.
TRUSTEES OF THE UNIV OF PAGenetics Core FacilitiesAttn: Jeffrey Griffin415 Curie Blvd., Suite 500Philadelphia, PA 19104-6145Links and Resources
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Tapan Ganguly, Ph.D. |
Director
|
215-573-7238
|
gangulyt@pennmedicine.upenn.edu
|
B16 Anat-Chem Bldg.
|
| Erik Toorens |
Technical Director
|
215-573-4832
|
toorens@pennmedicine.upenn.edu
|
502 Stellar-Chance Labs
|
| John Tobias |
Technical Director - Bioinformatics
|
215-573-4791
|
jtobias@pennmedicine.upenn.edu
|
| Price List |
| ► Illumina Sequencing on MiSeq (1) | |||
| Name | Description | Price | |
|---|---|---|---|
| Sq-MiSeq-V3-150 | Inquire | ||
