ALERT

 

Due to the evolving Coronavirus response, the hours of operation at Perelman School of Medicine cores and shared resources may be limited.  Please contact the Penn core facility directly for more information. 

(hide this warning on this page)

CNSC (Chemical and Nanoparticle Synthesis Core)

Overview of Services

The Chemical and Nanoparticle Synthesis Core (CNSC) was established by the Center for Targeted Therapeutics and Translational Nanomedicine (CT3N) to meet the chemical and nanoparticle design and synthesis needs of Penn investigators. The CNSC was formed with support from ITMAT (Clinical and Translational Science Award), the Perelman School of Medicine, the School of Engineering and Applied Science, and the Department of Chemistry (School of Arts and Sciences).

The CNSC supports researchers by providing in-house expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, and nanoparticle production and surface functionalization. Our chemists provide custom, problem-specific support for researchers in medical, chemical, and materials science fields. Specific services include:

  • Consultation and assistance with the design of chemical/medicinal compounds
  • In-house synthesis of chemical/medicinal compounds
  • Custom nanoparticle design and synthesis
  • Custom nanoparticle surface functionalization (-COOH, -NH2, PEG, -N3, Alkyne, etc.)
  • Polymer and dendrimer Synthesis

In addition to custom services, the CNSC also provides a Catalog of pre-made reactive metal chelates for radiolabeling and other imaging applications, reactive near-infrared imaging agents, hydrophobic and hydrophilic nanoparticles. A list of available products can be found under the ‘Catalog’ pull-down menu on the left.

To schedule an appointment with one of the CNSC chemists to initiate your next CNSC project or to submit a request, please send an email to CNSC@pennmedicine.upenn.edu and we will respond shortly. Please include a brief description of your project, including the chemical structure and amount needed, if known.

IP and Publication Policy

Intellectual Property (IP): For all projects submitted to the CNSC, the IP will belong entirely to the submitting party, not the CNSC or its employees.

Publications: If the CNSC produces a known chemical compound, nanoparticle, or polymer, we request that the core be acknowledged by the following (or similar) statement: “Compound X was provided by the Chemical and Nanoparticle Synthesis Core, University of Pennsylvania, PA 19104”, with appropriate reference to the published procedure.

If a new compound is produced and complete characterization data is required for publication, we request that the CNSC staff scientist(s) involved with the project be included as a co-author.

Leadership

Kido Nwe | Technical Director

Davit Jishkariani | Associate Technical Director

Location and hours of operation

Hours Location

Monday - Friday
9am - 5pm     
            

3400 Civic Center Boulevard, Building 421
10th Floor, Room 122
Philadelphia, PA 19104-5158

Links and Resources

Contacts

Name Role Phone Email Location
Andrew Tsourkas
Co-Director
 

 
atsourk@seas.upenn.edu
 

 
Jeffrey Winkler
Co-Director
 

 
winkler@sas.upenn.edu
 

 
Kido Nwe
Technical Director
 

 
CNSC@pennMedicine.upenn.edu
 

 
Davit Jishkariani
Associate Technical Director
 

 
davitj@pennmedicine.upenn.edu