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Rodent Metabolic Phenotyping Core

 

The mission of the Rodent Metabolic Phenotyping Core is to provide the necessary resources and expertise to allow investigators to perform state-of-the-art studies of metabolism in rodent models.

The Specific Aims of the RMPC

  • Provide access to state-of-the-art resources and expertise for rodent metabolic studies. Rodents have served as important models for human diseases and our understanding of diabetes, obesity and other metabolic disorders has increased tremendously as a result of dietary and genetic manipulations in these animals. In many cases, the standard techniques for phenotyping rodents are not accessible to individual investigators because they require expert surgical skills and facilities for infusion and handling of radioactive isotopes (e.g., clamps) or prohibitively expensive equipment that requires training and expertise to maintain (e.g., indirect calorimetry). By providing these services, the RMPC reduces duplication of expensive equipment and personnel, and ultimately limits research costs. These goals are well aligned with the overall mission of the Institute for Diabetes, Obesity and Metabolism to promote and facilitate research into diabetes and metabolism.
  • Provide individualized guidance and assistance for designing and implementing in vivo metabolic assays. A key function of the core is to make metabolic assays accessible to investigators who would otherwise not be able to perform such studies. In many cases, this involves providing guidance as to the selection of appropriate assays within the suite of services offered by the core, and we are happy to do this.

Support & Research Resource Identifier (RRID)

Kindly acknowledge the RMPC when presenting or publishing data obtained using our services. We are supported in part by NIH grant S10-OD025098 and the Cox Institute.

Our RRID is RRID:SCR_022427. Please cite us using this identifier when publishing your results. 

Please consider the following guidelines when determining whether co-authorship is warranted for core personnel: https://abrf.org/authorship-guidelines

Leadership 

Joseph A. Baur, Ph.D., Co-Director

Paul M. Titchenell, Ph.D., Co-Director

Corey D. Holman, Ph.D., Technical Director

Location

The Rodent Metabolic Phenotyping Core is located at Institute for Diabetes, Obesity, & Metabolism in the Smilow Center for Translational Research
TRC Rooms: 150-154
3400 Civic Center Boulevard - Building 421
Philadelphia, PA 19104-5160

Please ship samples to:

UPenn RMPC Attn: Corey Holman

12-174 Smilow Center for Translational Research
Perelman School of Medicine, University of Pennsylvania
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-516012-172

 Links and Resources

Contacts

Name Role Phone Email Location
Joseph Baur
Core Co-Director
 
215-746-4585 (office)
 
baur@pennmedicine.upenn.edu
 
12-114
 
Paul Titchenell
Core Co-Director
 
215-573-1875 (office)
 
ptitc@pennmedicine.upenn.edu
 
12-104
 
Corey Holman
Technical Director
 
978-844-4991
 
holmanc@pennmedicine.upenn.edu
 
12-174