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Clinical Research Informatics Core

Overview of Services

The Institute for Biomedical Informatics (IBI) Clinical Research Informatics Core (CIC) provides data brokering and analytics services of clinical data for clinical and translational research in which the goal is to learn actionable healthcare knowledge and develop impactful solutions for improving patient care. We specialize in data extraction, integration, standardization, and analytics of clinical data from the electronic health record (EHR) as well as research databases including PennG&P, Penn COVID-19 i2b2 database, and the IQVIA Medical Record Database using artificial intelligence, natural language processing (NLP), ontologies, machine learning, and visual analytics. We also provide translation of research products into healthcare operations through coordination of projects with Penn Medicine Corporate Information Services, Penn Data Analytics Center, and the Center for Applied Health Informatics. The IBI CIC is a member of the Penn-sponsored Honest Broker program.


Consultation services:

— Generate aggregate counts as prep for research
— Assess project feasibility, study design, and computational approaches
— Advise data management, security, privacy, compliance
— Assist with writing grant proposals and NIH Data Management Plans
— Provide guidance for preparing institute review board (IRB) protocols
— Advise coordination across other cores and centers sponsored through Penn’s Honest Brokering program including the Penn Medicine BioBank, Abramson Cancer Center Electronic Phenotyping Resource

Technical services:

— Broker clinical data from PennChart EHR, PennG&P, Penn COVID-19 i2b2 database, and the IQVIA Medical Record Database
— Define study variables, clinical phenotypes, and patient health outcomes
— Extract, transform, and load data into REDCap
— De-identify, extract, encode, and classify information from clinical notes using NLP
— Standardize clinical data using biomedical and biological ontologies
— Facilitate authorizations and data linkage with external data sources, e.g., national death index, claims data, geographical surveys, etc.
— Generate case/control datasets for clinical and translational research
— Develop and validate predictive models and visual analytic solutions
— Translate research products into healthcare operations and assess their impact as part of the Penn Learning Health System
— Facilitate appropriate data sharing and execution of NIH Data Management Plans

Fee Structure:

Low Complexity Project (<2 hours): $250 flat project fee
Moderate Complexity Project (2-8 hours): $750 flat project fee
High Complexity Project (>8 hours): $750 flat project fee + $125/hr for each hour exceeding 8
Very high complexity or extended duration projects handled by custom quote or negotiated salary support as % effort

Leadership:

Danielle L. Mowery PhD MS MS FAMIA
Scientific Director
Chief Research Informatics Officer
dlmowery@pennmedicine.upenn.edu

Research Resource Identifier (RRID)

Our RRID is: RRID:SCR_022409. Please cite us using this identifier when publishing your results. 

Leadership

Danielle Mowery PhD FAMIA Scientific Director
Emily Schriver MS Translational Data Scientist
Sunil Thomas MS Data Analyst Sr.
Sy Hwang MS NLP Data Scientist
Ashley Batugo BS Data Analyst Jr.
Selah Lynch MS Data Science Navigator

Location and hours of operation

Hours Location

9AM - 5PM 
Monday - Friday

370 Hamilton Walk
Philadelphia, PA 19104-6021

Links and Resources

  1. Clinical Research Informatics Core
  2. Institute for Biomedical Informatics

Contacts

Name Role Phone Email Location
Danielle Mowery PhD MS MS FAMIA

 

 
ibi-cic@lists.upenn.edu