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Quantitative Proteomics Resource Core


Please read about the merging of the Penn and CHOP proteomic cores here

Overview of Services

The Quantitative Proteomics Resource Core (QPRC) provides investigators access to the most advanced high-resolution mass-spectrometry-based proteomics technologies. These approaches are implemented with a broad variety of mass-spectrometry-based experiments to characterize and quantify proteins from complex biological samples.

See the instruction (Download)

Services include:

  • Protein identification from gel bands or solution samples
  • Single protein post-translational modification (PTM) analyses using Bottom Up 
  • Global proteome expression analyses from cells or tissues using label-free, SILAC or TMT quantification
  • Protein-protein or RNA-protein interaction experiments
  • Global histone PTM analysis
  • Custom analyses based on targets of interest (single target or proteome-wide)




  •QPRC Policy  Download

  •Frequently Asked Questions  Download 

  •(Co)-IP Sample Guidelines    Short version   Long version

   •Multiplex TMT Quantitation


    Workflow of  Global Proteome and Phosphoproteome 

   •N-linked glycosylation sites  download





Benjamin Garcia, Ph.D. | Core Director

Hyoungjoo Lee, Ph.D. | Technical Director


Location and hours of operation

Hours Location

Monday - Friday

9am - 5pm                      

 Room 9-179

Smilow Center for Translational Research University of Pennsylvania
3400 Civic Center Blvd.
Philadelphia, PA 19104-5157                                           

Links and Resources


Name Role Phone Email Location
Benjamin Garcia
Core Director
Room 9-124
Hyoungjoo Lee
Technical Director
Room 9-179
Katie Heer
Financial Coordinator
242 Anatomy Chemistry BLDG
Joseph Cesare
Research Specialist
Room 9-179