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Quantitative Proteomics Resource Core

The equipment and staff of the Penn QPRC have now physically and administratively merged with the CHOP Proteomics Core to provide a single, unified facility designed to meet the proteomics needs of the entire Penn/CHOP community.

Access to core services are available HERE

Read about the merging of the Penn and CHOP proteomic cores here

Overview of Services

The Quantitative Proteomics Resource Core (QPRC) provides investigators access to the most advanced high-resolution mass-spectrometry-based proteomics technologies. These approaches are implemented with a broad variety of mass-spectrometry-based experiments to characterize and quantify proteins from complex biological samples.

See the instruction (Download)

Services include:

  • Protein identification from gel bands or solution samples
  • Single protein post-translational modification (PTM) analyses using Bottom Up 
  • Global proteome expression analyses from cells or tissues using label-free, SILAC or TMT quantification
  • Protein-protein or RNA-protein interaction experiments
  • Global histone PTM analysis
  • Custom analyses based on targets of interest (single target or proteome-wide)

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Resources

 

  •QPRC Policy  Download

  •Frequently Asked Questions  Download 

  •(Co)-IP Sample Guidelines    Short version   Long version

   •Multiplex TMT Quantitation

    Guideline

    Workflow of  Global Proteome and Phosphoproteome 

   •N-linked glycosylation sites  download

 

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Location and hours of operation

Hours Location

Monday - Friday

9am - 5pm                      

 Room 9-179

Smilow Center for Translational Research University of Pennsylvania
3400 Civic Center Blvd.
Philadelphia, PA 19104-5157                                           

Links and Resources

Contacts

Name Role Phone Email Location